This ready-to-use training package is designed to provide HIV clinicians (including physicians, dentists, nurses, therapists and social workers, and counselors, specialists, and case managers) with an overview of the challenges and strategies for change in working with individuals living with HIV/AIDS and a diagnosis of a substance use disorder. The training package contains a PowerPoint presentation including pre- and post- knowledge tests, a case study and questions to spark discussion, a trainer guide with detailed notes for trainers, and a takeaway tip sheet for clinicians.