This ready-to-use slide set introduces substance use disorder providers to the issues of HIV and hepatitis C virus (HCV) screening and prevention. It emphasizes that the guiding principles of substance use care — harm reduction, screening and other prevention interventions, treatment initiation, and linkage to ongoing medical care — are similar to those of viral hepatitis and HIV care. All models focus on patient safety and wellness, with effective medication being critical for the individual’s health and for related public health benefits. The presentation, which takes approximately 30 minutes, can be given as a standalone training, or can be added to an existing training activity/program.